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use include order zyban of head trauma or prior seizure, central nervous system(CNS) tumor, the presence of severe hepatic cirrhosis, and concomitant medicationsthat lower seizure threshold.• Clinical situations: Circumstances associated with an increased seizure risk include,among others, excessive use of alcohol or sedatives order zyban benzodiazepines);addiction to opiates, cocaine, or stimulants; use of over-the-counter stimulants andanorectics; and diabetes treated with oral hypoglycemics or insulin.• Concomitant medications: order zyban medications (e.g., antipsychotics, antidepressants,theophylline, systemic order zyban order zyban order zyban to lower seizure threshold.Recommendations for Reducing the Risk of Seizure: Retrospective analysis of clinicalexperience gained during the development order zyban bupropion suggests that the risk of seizuremay be minimized if• the total daily dose of ZYBAN does not exceed 300 mg order zyban maximum recommendeddose order zyban smoking cessation), order zyban the recommended order zyban dose for most.
above 300 mg/day should not be used (see WARNINGS). order zyban order zyban be swallowed whole and not crushed, divided, or chewed. Treatment.
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